Co-encapsulation of Rifampicin and Isoniazid in Crude Soybean Lecithin Liposomes
نویسندگان
چکیده
منابع مشابه
Isoniazid- and rifampicin-induced thrombocytopenia
Treatment of tuberculosis has many side effects. Thrombocytopenia is a serious side effect of such treatment and occurs mostly due to rifampicin (RIF). There are very few reported cases of thrombocytopenia due to isoniazid (INH). An 18-year-old female patient was diagnosed with smear-positive pulmonary tuberculosis. A four-drug regimen [INH, RIF, ethambutol (EMB), and pyrazinamide (PZA)] was gi...
متن کاملInteraction of rifampicin and isoniazid with large unilamellar liposomes: spectroscopic location studies.
The location of isoniazid and rifampicin, two tuberculostatics commonly used for the treatment of Mycobacterium tuberculosis and Mycobacterium avium complex infectious diseases, in bilayers of dimyristoyl-L-alpha-phosphatidylcholine (DMPC) and dimyristoyl-L-a-phosphatidylglycerol (DMPG) have been studied by 1H NMR and fluorimetric methods. Steady-state fluorescence intensity and fluorescence en...
متن کاملSimultaneous spectrophotometric determination of Rifampicin, Isoniazid and Pyrazinamide in a single step
Three antituberculosis medications are investigated in this work consist of rifampicin, isoniazid and pyrazinamide. The ultra violet (UV) spectra of these compounds are overlapped, thus use of suitable chemometric methods are helpful for simultaneous spectrophotometric determination of them. A generalized version of net analyte signal standard addition method (GNASSAM) was used for determinatio...
متن کاملSimultaneous spectrophotometric determination of Rifampicin, Isoniazid and Pyrazinamide in a single step
Three antituberculosis medications are investigated in this work consist of rifampicin, isoniazid and pyrazinamide. The ultra violet (UV) spectra of these compounds are overlapped, thus use of suitable chemometric methods are helpful for simultaneous spectrophotometric determination of them. A generalized version of net analyte signal standard addition method (GNASSAM) was used for determinatio...
متن کاملLow isoniazid and rifampicin concentrations in TB/HIV co-infected patients in Uganda
INTRODUCTION There is limited data available on exposure to anti-tuberculosis (TB) drugs in this region. Peloquin has described reference ranges [1] however some studies have demonstrated that patients actually achieve concentrations below these ranges [2]. There is limited data about exposure to anti-TB drugs in the HIV/TB co-infected population in Sub-Saharan Africa. Our objective is to descr...
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ژورنال
عنوان ژورنال: South African Journal of Chemistry
سال: 2019
ISSN: 0379-4350,1996-840X
DOI: 10.17159/0379-4350/2019/v72a11